Zofran extravasation treatment
Information about Zofran.
Serotonin is produced largely in the gastrointestinal tractWhen a patient undergoes cancer treatmentradiation or chemotherapy drugs can cause specialized cells in the intestine to release serotoninZofran and the other 5-HT3 receptor antagonists work by preventing this serotonin from binding to 5-HT3 receptors.
FDA pregnancy category BThis medication is not expected to be harmful to an unborn babyTell your doctor if you are pregnant or plan to become pregnant during treatment.
To make sure you can safely take ondansetrontell your doctor if you have any of these other conditions:
Ondansetron is extensively metabolized in humanswith approximately 5of a radiolabeled dose recovered as the parent compound from the urineThe metabolites are observed in the urineThe primary metabolic pathway is hydroxylation on the indole ring followed by subsequent glucuronide or sulfate conjugation.
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while this condition can occur with any form and dosage of zofran, it is most closely linked with the intravenous iv 32 mg dosage.