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Hydrochlorothiazide crosses the placentaBased on the pharmacological mechanism of action of hydrochlorothiazide its use during the second and third trimester may compromise foeto-placental perfusion and may cause foetal and neonatal effects like icterusdisturbance of electrolyte balance and thrombocytopenia.
If you are not sure if prescriptions on line. any of the above applies to youtalk to your doctor or pharmacist before taking Zestoretic.
Discontinue as soon as possible when pregnancy is detectedaffects renin-angiotensin systemcausing oligohydramnioswhich may result in fetal injury and/or death.
Because of the risk of hypokalaemia the concomitant administration of hydrochlorothiazide and medicinal products that induce torsades de pointese.gsome antiarrhythmicssome anti-psychotics and other drugs known to induce torsades de pointesshould be used with caution.
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